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To determine the effect of pulmonary emphysema on the relationship between myocardial oxygen demand and delivery, we studied the following three groups of anesthetized open-chested dogs: 1) control, 2) emphysematous, and 3) healthy-matched. Myocardial oxygen demand was increased by the infusion of dobutamine and myocardial oxygen delivery by the infusion of blood and increased by increasing left atrial pressure. As the increase in both myocardial oxygen demand and oxygen delivery was greater in the emphysematous group than in the healthy group, we conclude that there is an increased need for oxygen by the myocardium in emphysema. The possible causes of this increased myocardial oxygen demand in emphysema are discussed.Carotid intima-media thickness in patients with nonalcoholic fatty liver disease. In this study we investigated the association of nonalcoholic fatty liver disease (NAFLD) with carotid intima-media thickness (CIMT). 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